Lucrări ştiinţifice
Emergence of bedaquiline-resistance in a high-burden country of tuberculosis.
Chesov E., Chesov D, Maurer FP, Andres Sönke, Christian Utpatel, Ivan Barilar , Ana Donica , Maja Reimann, Stefan Niemann, Christoph Lange, Valeriu Crudu , Jan Heyckendorf, Matthias Merker.
Integrating landmark modeling framework and machine learning algorithms for dynamic prediction of tuberculosis treatment outcomes
Maryam Kheirandish, Donald Catanzaro, Valeriu Crudu, Shengfan Zhang.
Phylogeography and transmission of M. tuberculosis in Moldova
Chongguang Yang, Benjamin Sobkowiak , Vijay Naidu, Alexandru Codreanu, Nelly Ciobanu, Kenneth S. Gunasekera, Melanie H. Chitwood, Sofia Alexandru, Stela Bivol, Marcus Russi, Joshua Havumaki, Patrick Cudahy, Heather Fosburgh, Christopher J. Allender, Heather Centner, David M. Engelthaler, Nicolas A. Menzies, Joshua L. Warren, Valeriu Crudu#, Caroline Colijn, Ted Cohen.
Rapid Detection of Extensively Drug-Resistant Tuberculosis in Clinical Samples Using a Novel Tabletop Platform: Protocol for a Prospective Clinical Study
Naomi Hillery, MPH; Marva Seifert, ; Donald G Catanzaro, ; Symone McKinnon, MA; Rebecca E Colman, Peter G Chiles1, Dumitru Chesov, Nelly Ciobanu, Christopher Hagan, Valeriu Crudu, Antonino Catanzaro, Timothy C Rodwell.
Xpert XDR Trial Consortium. Clinical evaluation of the Xpert MTB/XDR assay for rapid detection of isoniazid, fluoroquinolone, ethionamide and second-line drug resistance: A cross-sectional 3 multicentre diagnostic accuracy study.
Adam Penn-Nicholson, Sophia B. Georghiou, Nelly Ciobanu, Mubin Kazi, Manpreet Bhalla, Anura David, Francesca Conradie, Morten Ruhwald, Valeriu Crudu, Camilla Rodrigues, Vithal Prasad Myneedu, Lesley Scott, Claudia M Denkinger, Samuel G Schumacher, Lancet Infect Dis 2021.Published Online October 7, 2021 doi: .
Predicting resistance to fluoroquinolones among patients with rifampicin-resistant tuberculosis using machine learning methods.
Shiying You, Melanie H. Kenneth S. Gunasekera, Valeriu Crudu, Alexandru Codreanu, Nelly Ciobanu, Jen Furin, Ted Cohen, Joshua L. Warren, Reza Yaesoubi.
Transcontinental spread and evolution of Mycobacterium tuberculosis W148 European/Russian clade towards extensively drug resistant tuberculosis.
Matthias Merker, Maxime Barbier, Helen Cox, Jean-Philippe Rasigade, Silke Feuerriege, Thomas A. Kohl, Egor Shitikov, Kadri Klaos, Cyril Gaudin1, Rudy Antoine, Roland Die, Sonia Borrell, Sebastien Gagneux, Vladyslav Nikolayevskyy, Sönke Andre, Valeriu Crudu, Ulrich Nübel, Philip Supp, Stefan Niemann
Genotype to phenotype: variable resistance levels in clinical Mycobacterium tuberculosis complex strains caused by resistance mutations
Iris Finci A, Audrey AlbertiniB, Matthias Merker C, Sönke Andres, Nino Bablishvili, Ivan Barilar, Tatiana Cáceres, Valeriu Crudu, Eduardo Gotuzzo, Nchimunya Hapeel, Harald Hoffmann, Christine Hoogland, Thomas Kohl, Katharina Kranzer, Anna Mantsoki, Florian P. Maurer, Mark P. Nicol, Ecaterina Noroc, Sara Plesnik, Timothy Rodwell, Morten Ruhwald, Theresa Sadvidge, Max Salfinger, Elizabeth Streicher, Nestani Tukvadze, Rob Warren, Widaad ZemanayA, Stefan Niemann, Claudia M. Denkinger.
Evolution and emergence of multidrug-resistant Mycobacterium tuberculosis in Chisinau, Moldova. Microbial Genomics
Tyler S. Brown, Vegard Eldholm, Ola Brynildsrud, Magnus Osnes, Natalie Levy, James Stimson, Caroline Colijn, Sofia Alexandru, Ecaterina Noroc, Nelly Ciobanu, Valeriu Crudu, Ted Cohen and Barun Mathema.
Evolution and emergence of multidrug-resistant Mycobacterium tuberculosis in Chisinau, Moldova
Tyler S. Brown, Vegard Eldholm, Ola Brynildsrud, Magnus Osnes, Natalie Stennis, James Stimson,Caroline Colijn, Sofia Alexandru, Ecaterina Noroc, Nelly Ciobanu, Valeriu Crudu, Ted Cohen, Barun Mathema.
Nivelul de rezistență fenotipică și paternul de mutații genice a M.tuberculosis
Nelly Ciobanu, Alexandru Codreanu, Nadejda Țurcan și Valeriu Crudu.
Study of antituberculosis activity of the cyclodextrins particles loaded with juglone.
Natalia Sucman, Livia Uncu, Valeriu Crudu, Nelly Ciobanu, Alexandru Codreanu, Vladimir Valica, Fliur Macaev.
Evaluarea activității antifungice și antibacteriene a unui nou derivate nesaturat de 1,2,4-triazol (Nitrotriazon).
Maria Drumea, Eugenia Stingaci, Livia Uncu, Valeriu Crudu,Vladimir Valica, Fliur Macaev.
Genomic sequence characteristics and the empiric accuracy of short-read sequencing.
Maximillian Marin, Roger Vargas Jr, Michael Harris, Brendan Jeffrey, L. Elaine Epperson, Melissa Smith4, Irina Oussenko, David Durbin, Michael Strong, Max Salfinger, Irada Akhundova, Sergo Vashakidze, Valeriu Crudu, Alex Rosenthal, and Maha Reda Farhat.
Laboratory costs of diagnosing TB in a high multidrug-resistant TB setting
Cates L, Crudu V, Codreanu A, Ciobanu N, Fosburgh H, Cohen T, Menzies
Impact of bedaquiline on treatment outcomes of multidrug-resistant tuberculosis in a high-burden country.
Dumitru Chesov, Jan Heyckendorf, Sofia Alexandru, Ana Donica, Elena Chesov, Maja Reiman, Valeriu Crudu, Victor Botnaru, Christoph Lange.
Molecular Detection of Mycobacterium tuberculosis in Oral Mucosa from Patients with Presumptive Tuberculosis.
Molina-Moya B, Ciobanu N, Hernandez M, Prat-Aymerich C, Crudu V, Adams ER, Codreanu A, Sloan DJ, Cuevas LE, Dominguez J.